Distinctiveness of Mycobacterium tuberculosis genotypes from human immunodeficiency virus type 1-seropositive and -seronegative patients in Lima, Peru

被引:26
作者
Ahmed, N
Caviedes, L
Alam, M
Rao, KR
Sangal, V
Sheen, P
Gilman, RH
Hasnain, SE
机构
[1] CDFD, Hyderabad 500076, Andhra Pradesh, India
[2] Natl Inst Immunol, New Delhi 110067, India
[3] Indian Inst Sci, Jawaharlal Nehru Ctr Adv Sci Res, Bangalore 560012, Karnataka, India
[4] Univ Peruana Cayetano Heredia, Dept Pathol, Lima, Peru
[5] AB PRISMA, Lima, Peru
[6] Johns Hopkins Sch Publ Hlth & Hyg, Baltimore, MD USA
关键词
D O I
10.1128/JCM.41.4.1712-1716.2003
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Genotypic analysis of Mycobacterium tuberculosis isolates obtained from human immunodeficiency virus type 1 (HIV-1)-seropositive (n = 80) and -seronegative (u = 25) patients from Lima, Peru, revealed two distinct genotypes correlating with the host immune status. While the level of intrastrain diversity of DNA fingerprints of HIV-seropositive isolates was less pronounced, these isolates showed many clonal groupings.
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页码:1712 / 1716
页数:5
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