BABELOMICS:: a systems biology perspective in the functional annotation of genome-scale experiments

被引:197
作者
Al-Shahrour, Fatima
Minguez, Pablo
Tarraga, Joaquin
Montaner, David
Alloza, Eva
Vaquerizas, Juan M.
Conde, Lucia
Blaschke, Christian
Vera, Javier
Dopazo, Joaquin
机构
[1] CIPF, Bioinformat Dept, E-46013 Valencia, Spain
[2] CIPF, Funct Genom Node, INB, E-46013 Valencia, Spain
[3] Bioalma, E-28760 Madrid, Spain
[4] INB, BSC, E-08034 Barcelona, Spain
关键词
D O I
10.1093/nar/gkl172
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We present a new version of Babelomics, a complete suite of web tools for functional analysis of genome- scale experiments, with new and improved tools. New functionally relevant terms have been included such as CisRed motifs or bioentities obtained by text- mining procedures. An improved indexing has considerably speeded up several of the modules. An improved version of the FatiScan method for studying the coordinate behaviour of groups of functionally related genes is presented, along with a similar tool, the Gene Set Enrichment Analysis. Babelomics is now more oriented to test systems biology inspired hypotheses. Babelomics can be found at http://www.babelomics.org.
引用
收藏
页码:W472 / W476
页数:5
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