NNDB: the nearest neighbor parameter database for predicting stability of nucleic acid secondary structure

被引：358

作者：

Turner, Douglas H. ^{[3
,4
]}

Mathews, David H. ^{[1
,2
]}

机构：

[1] Univ Rochester, Med Ctr, Dept Biochem & Biophys, Rochester, NY 14642 USA

[2] Univ Rochester, Med Ctr, Ctr RNA Biol, Rochester, NY 14642 USA

[3] Univ Rochester, Dept Chem, Rochester, NY 14627 USA

[4] Univ Rochester, Ctr RNA Biol, Rochester, NY 14627 USA

来源：

NUCLEIC ACIDS RESEARCH | 2010年 / 38卷

基金：

美国国家卫生研究院;

关键词：

THERMODYNAMIC PARAMETERS; RNA; ALGORITHM;

D O I：

10.1093/nar/gkp892

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Nearest Neighbor Database (NNDB, http://rna.urmc.rochester.edu/NNDB) is a web-based resource for disseminating parameter sets for predicting nucleic acid secondary structure stabilities. For each set of parameters, the database includes the set of rules with descriptive text, sequence-dependent parameters in plain text and html, literature references to experiments and usage tutorials. The initial release covers parameters for predicting RNA folding free energy and enthalpy changes.

引用

页码：D280 / D282

页数：3

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