Thalamic deep brain stimulation activates the cerebellothalamocortical pathway

被引：45

作者：

Molnar, GF

Sailer, A

Gunraj, CA

Lang, AE

Lozano, AM

Chen, R

机构：

[1] Univ Toronto, Krembil Neurosci Ctr, Div Neurol, Toronto, ON, Canada

[2] Univ Toronto, Krembil Neurosci Ctr, Div Neurosurg, Toronto, ON, Canada

[3] Univ Toronto, Univ Hlth Network, Toronto Western Res Inst, Toronto, ON, Canada

来源：

NEUROLOGY | 2004年 / 63卷 / 05期

关键词：

D O I：

10.1212/01.WNL.0000137419.85535.C7

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

To investigate the mechanism of action of deep brain stimulation (DBS), the authors studied the effects of thalamic DBS on the cerebellothalamocortical (CTC) pathway. With DBS turned off, excitability of the CTC pathway was reduced. Turning DBS on resulted in facilitation of the CTC pathway. Therefore, thalamic DBS appears to activate rather than inhibit the target area.

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页码：907 / 909

页数：3

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