Applicability of interrupter resistance measurements using the MicroRint® in daily practice

被引:30
作者
Arets, HGM [1 ]
Brackel, HJL [1 ]
van der Ent, CK [1 ]
机构
[1] Univ Utrecht, Ctr Med, Dept Pediat Pulm, NL-3508 AB Utrecht, Netherlands
关键词
asthma; lung function; children; interrupter technique; airway resistance;
D O I
10.1053/rmed.2002.1452
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This study was performed to evaluate the applicability of a simple device (Micro Rint((R))) for measuring airway resistance, to derive normal values and to compare values with maximal expiratory flow volume (MEFV) parameters in asthmatic and healthy children. Repetitive R-int measurements were performed in 125 healthy children and 107 asthmatic children (age range 0.8- 16.8 years). In 42 asthmatic patients R-int and MEFV values were compared and in 29 asthmatic children bronchodilation testing was performed. Successful R-int measurements were possible in 91% of the children. The mean coefficient of variation of repeated measurements was 71( +/-6.1)% R-int values of healthy children showed a significant curvilinear correlation with age (r=-0.80, P < 0.001) and height (r=-0.81, P < 0.001). In asthmatic and healthy children R-int values were comparable. A significant inverse correlation was found between R-int and MEFV values (for FEVI and R-int r=-0.80, P < 0.001). After bronchodilation there was a significant increase in FEVI and decrease in R-int but changes between the two parameters did not correlate. In conclusion, the interrupter technique is feasible and repeatable in children and has a significant correlation with other parameters of airway caliber, Baseline values do not discriminate healthy from asthmatic children. (C) 2003 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:366 / 374
页数:9
相关论文
共 30 条
[1]  
ARETS HGM, 2002, IN PRESS EUR RESP J
[2]   INTERNATIONAL STUDY OF ASTHMA AND ALLERGIES IN CHILDHOOD (ISAAC) - RATIONALE AND METHODS [J].
ASHER, MI ;
KEIL, U ;
ANDERSON, HR ;
BEASLEY, R ;
CRANE, J ;
MARTINEZ, F ;
MITCHELL, EA ;
PEARCE, N ;
SIBBALD, B ;
STEWART, AW ;
STRACHAN, D ;
WEILAND, SK ;
WILLIAMS, HC .
EUROPEAN RESPIRATORY JOURNAL, 1995, 8 (03) :483-491
[3]   MEASUREMENT OF ALVEOLAR PRESSURE IN CLOSED-CHEST DOGS DURING FLOW INTERRUPTION [J].
BATES, JHT ;
ABE, T ;
ROMERO, PV ;
SATO, J .
JOURNAL OF APPLIED PHYSIOLOGY, 1989, 67 (01) :488-492
[4]   RESPIRATORY MECHANICS IN THE NORMAL DOG DETERMINED BY EXPIRATORY FLOW INTERRUPTION [J].
BATES, JHT ;
BROWN, KA ;
KOCHI, T .
JOURNAL OF APPLIED PHYSIOLOGY, 1989, 67 (06) :2276-2285
[5]   Pre/postbronchodilator interrupter resistance values in healthy young children [J].
Beydon, N ;
Amsallem, F ;
Bellet, M ;
Boule, M ;
Chaussain, M ;
Denjean, A ;
Matran, R ;
Wuyam, B ;
Alberti, C ;
Gaultier, C .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2002, 165 (10) :1388-1394
[6]   Lung function measurement in awake young children [J].
Bisgaard, H ;
Klug, B .
EUROPEAN RESPIRATORY JOURNAL, 1995, 8 (12) :2067-2075
[7]   STATISTICAL METHODS FOR ASSESSING AGREEMENT BETWEEN TWO METHODS OF CLINICAL MEASUREMENT [J].
BLAND, JM ;
ALTMAN, DG .
LANCET, 1986, 1 (8476) :307-310
[8]   A portable device based on the interrupter technique to measure bronchodilator response in schoolchildren [J].
Bridge, PD ;
Lee, H ;
Silverman, M .
EUROPEAN RESPIRATORY JOURNAL, 1996, 9 (07) :1368-1373
[9]   Measurement of airway resistance using the interrupter technique in preschool children in the ambulatory setting [J].
Bridge, PD ;
Ranganathan, S ;
McKenzie, SA .
EUROPEAN RESPIRATORY JOURNAL, 1999, 13 (04) :792-796
[10]  
[British Thoracic Society Brit. Paediatric Association Research Unit of the Royal College of Physicians of London King's Fund Centre National Asthma Campaign Royal College of General Practitioners General Practitioners in Asthma Group British Association of Accident and Emergency Medicine British Paediatric Respiratory Group], 1993, THORAX, V48, pS1