TRAIL and immunity: more than a license to kill tumor cells

被引:12
作者
Corazza, N [1 ]
Brumatti, G [1 ]
Schaer, C [1 ]
Cima, I [1 ]
Wasem, C [1 ]
Brunner, T [1 ]
机构
[1] Univ Bern, Inst Pathol, Div Immunopathol, CH-3010 Bern, Switzerland
关键词
D O I
10.1038/sj.cdd.4401542
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The continuously growing family of structurally related proteins of the tumor necrosis factor (TNF) family has received enormous scientific attention due to their important role in the regulation of cell activation, survival death and many other physiological and pathophysiological events (reviewed in Locksley et al.1). In this News and Commentary, we will focus on the only recently recognized and appreciated role of TNF-related apoptosis-inducing ligand (TRAIL) in regulating various physiological and pathophysiological processes involving immune cells. © 2004, Nature Publishing Group. All rights reserved.
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收藏
页码:S122 / S125
页数:4
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