Image analysis in patients with cancer studied with a combined PET and CT scanner

被引:125
作者
Charron, M
Beyer, T
Bohnen, NN
Kinahan, PE
Dachille, M
Jerin, J
Nutt, R
Meltzer, CC
Villemagne, V
Townsend, DW
机构
[1] Univ Pittsburgh, Med Ctr, Pittsburgh, PA USA
[2] Univ Pittsburgh, PET Facil, Pittsburgh, PA USA
[3] CTI PET Syst, Knoxville, TN USA
关键词
computed tomography; PET; image fusion; oncology;
D O I
10.1097/00003072-200011000-00010
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Purpose: To compare combined whole-body PET and CT images of different cancers with PET images alone. Materials and Methods: Thirty-two patients with known or possible cancers were examined using a combined positron emission tomographic (PET) and computed tomographic (CT) scanner. All data were acquired using this same combined scanner. After an injection of F-18 fluorodeoxyglucose (FDG), noncontrast helical CT imaging of the neck, chest, abdomen, or pelvis was performed. The spiral CT was followed by a PET scan covering the same axial extent as the CT. Results: Coregistered PET-CT images identified and localized 55 lesions. In 10 patients (31%), areas with variable amounts of normal physiologic FDG uptake were distinguished from potential uptake of FDG in a nearby neoplastic lesion. Improved localization was achieved in 9 patients (for a total of 13 lesions, or 24%). Conclusion: Combined PET-CT images appear more effective than PET images alone to localize precisely neoplastic lesions and to distinguish normal variants from juxtaposed neoplastic lesions.
引用
收藏
页码:905 / 910
页数:6
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