TRP channel knockout mice lose their cool

被引：43

作者：

Chung, Man-Kyo

Caterina, Michael J. ^{[1
]}

机构：

[1] Johns Hopkins Sch Med, Dept Biol Chem, Baltimore, MD 21205 USA

[2] Johns Hopkins Sch Med, Dept Neurosci, Baltimore, MD 21205 USA

[3] Johns Hopkins Sch Med, Ctr Sensory Biol, Baltimore, MD 21205 USA

来源：

NEURON | 2007年 / 54卷 / 03期

关键词：

D O I：

10.1016/j.neuron.2007.04.025

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Heat and cold transduction by peripheral sensory neurons is a fundamental step in the avoidance of dangerous thermal extremes. In this issue of Neuron, Dhaka et al. and Colburn et al. report that mice lacking the cold- and menthol-gated ion channel TRPM8 exhibit deficient behavioral responses to cold temperatures.

引用

收藏

页码：345 / 347

页数：3

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