Palladium-catalyzed intramolecular coupling of vinyl halides and ketone enolates, synthesis of bridged azabicyclic compounds

被引：92

作者：

Solé, D ^{[1
]}

Peidró, E ^{[1
]}

Bonjoch, J ^{[1
]}

机构：

[1] Univ Barcelona, Fac Pharm, Organ Chem Lab, E-08028 Barcelona, Spain

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 15期

关键词：

D O I：

10.1021/ol005973i

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] The palladium-mediated intramolecular coupling of amino-tethered vinyl halides and ketone enolates is a useful methodology for the synthesis of nitrogen heterocycles and constitutes a new synthetic entry to the 2-azabicyclo[3.3.1]nonane framework, A study about the reaction conditions and the scope of the process is reported.

引用

页码：2225 / 2228

页数：4

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