A novel route to the geissoschizine skeleton: The influence of ligands on the diastereoselectivity of the Heck cyclization

被引：35

作者：

Birman, VB ^{[1
]}

Rawal, VH ^{[1
]}

机构：

[1] Univ Chicago, Dept Chem, Chicago, IL 60637 USA

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 40期

关键词：

D O I：

10.1016/S0040-4039(98)01591-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A concise, novel route to the geissoschizine skeleton has been developed. The key step involves a Heck cyclization reaction, which was found to lead to opposite diastereomers, (+/-)-8 or (+/-)-9, depending on the reaction conditions. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：7219 / 7222

页数：4

共 24 条

[1]

BANKS BJ, 1981, J TETRAHEDRON LETT, V22, P1631

[2] A concise, stereoselective synthesis of (+/-)-geissoschizine [J].