Characterisation of a sugar epimerase enzyme involved in the biosynthesis of a vancomycin-group antibiotic

被引：20

作者：

Kirkpatrick, PN

Scaife, W

Hallis, TM

Liu, H

Spencer, JB

Williams, DH

机构：

[1] Univ Cambridge, Cambridge Ctr Mol Recognit, Dept Chem, Cambridge CB2 1EW, England

[2] Univ Minnesota, Dept Chem, Minneapolis, MN 55455 USA

来源：

CHEMICAL COMMUNICATIONS | 2000年 / 17期

关键词：

D O I：

10.1039/b004463f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An enzyme involved in the biosynthesis of the 4-epi-vancosamine substituents of a vancomycin group antibiotic has been expressed and its role as a TDP-4-keto-6-deoxyglucose-3,5-epimerase demonstrated.

引用

页码：1565 / 1566

页数：2

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