Radiation esophagitis: Predictive factors and preventive strategies

被引:39
作者
Bradley, J
Movsas, B
机构
[1] Washington Univ, Sch Med, Dept Radiat Oncol, Alvin J Siteman Canc Ctr, St Louis, MO 63110 USA
[2] Fox Chase Canc Ctr, Dept Radiat Oncol, Philadelphia, PA 19111 USA
关键词
D O I
10.1016/j.semradonc.2004.06.003
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Radiation esophagitis remains the primary dose-limiting acute toxicity in the radiotherapeutic management of thoracic neoplasms. Improved understanding of this toxicity will facilitate dose escalation and enhancement of the therapeutic ratio. This article reviews the predictive factors and preventive strategies for radiation esophagitis. In particular, clinical and dosimetric studies predicting the risk of radiation esophagitis are analyzed. The critical impact of chemotherapy on radiation esophagitis is characterized. Preventive strategies to minimize this toxicity also are explored. Overall, this article reviews the current understanding of radiation toxicity for the esophagus. © 2004 Elsevier Inc. All rights reserved.
引用
收藏
页码:280 / 286
页数:7
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