siRNAs and DNA methylation: seedy epigenetics

被引:91
作者
Mosher, Rebecca A. [1 ]
Melnyk, Charles W. [1 ]
机构
[1] Univ Cambridge, Dept Plant Sci, Cambridge CB2 3EA, England
基金
加拿大自然科学与工程研究理事会;
关键词
RNA-POLYMERASE-IV; ZEA-MAYS L; ARABIDOPSIS-THALIANA; LAND PLANTS; TRANSPOSABLE ELEMENTS; BINDING PROTEIN; GENE-EXPRESSION; POLYCOMB GENE; ENDOSPERM; DEMETHYLATION;
D O I
10.1016/j.tplants.2010.01.002
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
To understand how DNA sequence is translated to phenotype we must understand the epigenetic features that regulate gene expression. Recent research illuminates the complex interactions between DNA methylation, small RNAs, silencing of transposable elements, and genomic imprinting in the Arabidopsis (Arabidopsis thaliana) seed. These studies suggest that transposable elements reactivated in specific cells of the gametophyte and seed might enhance silencing of transposable elements in the germline and embryo. By sacrificing genomic integrity these cells might make an epigenetic rather than genetic contribution to the progeny. This research could have implications for interspecies hybridization, the evolution of genomic imprinting, and epigenetic communication from plant to progeny.
引用
收藏
页码:204 / 210
页数:7
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