Hormesis - Basic, generalizable, central to toxicology and a method to improve the risk-assessment process

被引：19

作者：

Calabrese, EJ ^{[1
]}

机构：

[1] Univ Massachusetts, Sch Publ Hlth, Amherst, MA 01003 USA

来源：

INTERNATIONAL JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH | 2004年 / 10卷 / 04期

关键词：

hormesis; U-shaped; j-shaped; biphasic; low doses; stimulatory; risk assessment;

D O I：

10.1179/oeh.2004.10.4.466

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Hormesis, a dose-response phenomenon characterized by a low-dose stimulation and a high-dose inhibition, has been the object of controversy due to its challenging of basic understandings of the dose-response relationship and implications for risk assessment. The author addresses issues relating to the definition of hormesis, the relationship of hormesis to risk assessment and risk management, and the generalizability of hormesis within the toxicological literature.

引用

页码：466 / 467

页数：2

共 11 条

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