MR imaging-guided focused ultrasound surgery of uterine leiomyomas: A feasibility study

被引：466

作者：

Tempany, CMC

Stewart, EA

McDannold, N

Quade, BJ

Jolesz, FA

Hynynen, K

机构：

[1] Harvard Univ, Brigham & Womens Hosp, Sch Med, Dept Radiol, Boston, MA 02115 USA

[2] Harvard Univ, Brigham & Womens Hosp, Sch Med, Dept Obstet & Gynecol, Boston, MA 02115 USA

[3] Harvard Univ, Brigham & Womens Hosp, Sch Med, Dept Pathol, Boston, MA 02115 USA

来源：

RADIOLOGY | 2003年 / 226卷 / 03期

关键词：

leiomyoma; magnetic resonance (MR); thermometry; ultrasound; (US); focused; therapeutic; uterine neoplasms; MR; US;

D O I：

10.1148/radiol.2271020395

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

The feasibility and safety of magnetic resonance (MR) imaging-guided focused ultrasound surgery for uterine leiomyomas is reported. Sequential sonications were delivered to nine targets. Temperature-sensitive phase-difference MR imaging monitored the location of the focus and measured tissue temperature elevations, ensuring therapeutic dose. MR images and hysterectomy specimens were evaluated. Six leiomyomas received full therapeutic doses, and 98.5% of the sonications were visualized. MR thermometry was successful in all sonications and cases. Focal necrotic lesions were seen in all cases at MR, and five were pathologically confirmed. MR imaging-guided focused ultrasound causes thermocoagulation and necrosis in uterine leiomyomas and is feasible and safe, without serious consequences. (C) RSNA, 2003.

引用

页码：897 / 905

页数：9

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