Neurobiology: The acid test for resting potassium channels

被引:15
作者
Brown, DA [1 ]
机构
[1] UCL, Dept Pharmacol, London WC1E 6BT, England
关键词
D O I
10.1016/S0960-9822(00)00532-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The K(+) channels that generate the resting potential of mammalian neurons have been difficult to identify and characterize. Recent experiments on hypoglossal motoneurons and cerebellar granule cells suggest that the resting current in these neurons is carried by TASK-1, a member of the twin-pore family of K(+) channels. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:R456 / R459
页数:4
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