Preparation and antibacterial activity of Fe3O4@Ag nanoparticles

被引：481

作者：

Gong, Ping ^{[1
]}

Li, Huimin ^{[1
]}

He, Xiaoxiao ^{[1
]}

Wang, Kemin ^{[1
]}

Hu, Jianbing ^{[1
]}

Tan, Weihong ^{[1
]}

Zhang, Shouchun ^{[1
]}

Yang, Xiaohai ^{[1
]}

机构：

[1] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Biomed Engn Ctr, Changsha 410082, Peoples R China

来源：

NANOTECHNOLOGY | 2007年 / 18卷 / 28期

关键词：

D O I：

10.1088/0957-4484/18/28/285604

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Bifunctional Fe3O4@ Ag nanoparticles with both superparamagnetic and antibacterial properties were prepared by reducing silver nitrate on the surface of Fe3O4 nanoparticles using the water-in-oil microemulsion method. Formation of well-dispersed nanoparticles with sizes of 60 +/- 20 nm was confirmed by transmission electron microscopy and dynamic light scattering. X-ray diffraction patterns and UV-visible spectroscopy indicated that both Fe3O4 and silver are present in the same particle. The superparamagnetism of Fe3O4@Ag nanoparticles was confirmed with a vibrating sample magnetometer. Their antibacterial activity was evaluated by means of minimum inhibitory concentration value, flow cytometry, and antibacterial rate assays. The results showed that Fe3O4@Ag nanoparticles presented good antibacterial performance against Escherichia coli (gram-negative bacteria), Staphylococcus epidermidis (gram-positive bacteria) and Bacillus subtilis ( spore bacteria). Furthermore, Fe3O4@Ag nanoparticles can be easily removed from water by using a magnetic field to avoid contamination of surroundings. Reclaimed Fe3O4@Ag nanoparticles can still have antibacterial capability and can be reused.

引用

页数：7

共 38 条

[1] An in vitro assessment of the antibacterial properties and cytotoxicity of nanoparticulate silver bone cement [J].