In vitro study of oxytetracycline adsorption on activated charcoal

被引：16

作者：

Alegakis, AK

Tzatzarakis, MN

Tsatsakis, AM ^{[1
]}

Vlachonikolis, IG

Liakou, V

机构：

[1] Univ Crete, Toxicol Lab, Sch Med, Heraklion 71409, Crete, Greece

[2] Univ Crete, Biostat Unit, Sch Med, Heraklion 71409, Crete, Greece

[3] Venizelion Hosp, Microbiol Lab, Heraklion 71110, Crete, Greece

来源：

JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES | 2000年 / 35卷 / 05期

关键词：

in vitro; oxytetracycline; activated charcoal; adsorption capacity;

D O I：

10.1080/03601230009373292

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

In vitro adsorption experiments simulating pH in gastric environment and using Langmuir isotherm, showed that 408 mg of oxytetracycline was adsorbed per gram of activated charcoal. Langmuir isotherm fitted adsorption data better than a Freundlich isotherm. Freundlich isotherm showed a specific adsorption capacity of 518 mg/g for activated charcoal. Both isotherm parameters indicated a strong oxytetracycline adsorption on activated charcoal in terms of quantity and binding strength. The results demonstrate that: the concomitant use of oxytetracyline and activated charcoal should be avoided.

引用

页码：559 / 569

页数：11

共 19 条

[1] The effect of polyethylene glycol on the charcoal adsorption of chlorpromazine studied by ion selective electrode potentiometry [J].