Regioselective N-9 arylation of purines employing arylboronic acids in the presence of Cu(II)

被引：71

作者：

Bakkestuen, AK ^{[1
]}

Gundersen, LL ^{[1
]}

机构：

[1] Univ Oslo, Dept Chem, N-0315 Oslo, Norway

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 16期

关键词：

arylation; boron and compounds; copper and compounds; purines; regiocontrol;

D O I：

10.1016/S0040-4039(03)00576-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

9-Arylpurines are efficiently formed with complete regioselectivity when purines are treated with arylboronic acids in the presence of copper(II) acetate. A variety of substituents on both coupling partners are well tolerated. (C) 2003 Elsevier Science Ltd. All rights reserved.

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页码：3359 / 3362

页数：4

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