Expression of the Kruppel-like zinc finger gene biklf during zebrafish development

被引:32
作者
Kawahara, A [1 ]
Dawid, IB [1 ]
机构
[1] NICHHD, Mol Genet Lab, NIH, Bethesda, MD 20892 USA
基金
日本学术振兴会;
关键词
biklf; Kruppel-like factor; blood islands; BMP signaling;
D O I
10.1016/S0925-4773(00)00404-4
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The zebrafish biklf gene encodes a novel Kruppel-like transcription factor containing three contiguous zinc fingers at the C-terminus. Expression of biklf is detected from the shield stage onward in the developing prechordal plate, and as a 'baseball seam'-like lateral stripe beginning at the end of gastrulation. The latter expression domain is suppressed in the swirl mutant in which bmp2b is disrupted. At the 5-somite stage the lateral expression domain separates into two distinct stripes, one in the ectoderm, the other in blood islands in the lateral plate mesoderm. Blood island staining of biklf continues through somitogenesis as the most prominent area of biklf expression. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:173 / 176
页数:4
相关论文
共 18 条
[1]   Dissecting hematopoiesis and disease using the zebrafish [J].
Amatruda, JF ;
Zon, LI .
DEVELOPMENTAL BIOLOGY, 1999, 216 (01) :1-15
[2]  
ANDERSON KP, 1995, MOL CELL BIOL, V15, P5957
[3]   Activation of β-globin promoter by erythroid Kruppel-like factor [J].
Asano, H ;
Stamatoyannopoulos, G .
MOLECULAR AND CELLULAR BIOLOGY, 1998, 18 (01) :102-109
[4]   INTRAEMBRYONIC HEMATOPOIETIC-CELL MIGRATION DURING VERTEBRATE DEVELOPMENT [J].
DETRICH, HW ;
KIERAN, MW ;
CHAN, FY ;
BARONE, LM ;
YEE, K ;
RUNDSTADLER, JA ;
PRATT, S ;
RANSOM, D ;
ZON, LI .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (23) :10713-10717
[5]   REGIONAL EXPRESSION OF 3 HOMEOBOX TRANSCRIPTS IN THE INNER-EAR OF ZEBRAFISH EMBRYOS [J].
EKKER, M ;
AKIMENKO, MA ;
BREMILLER, R ;
WESTERFIELD, M .
NEURON, 1992, 9 (01) :27-35
[6]  
Kishimoto Y, 1997, DEVELOPMENT, V124, P4457
[7]   SCL/Tal-1 transcription factor acts downstream of cloche to specify hematopoietic and vascular progenitors in zebrafish [J].
Liao, EC ;
Paw, BH ;
Oates, AC ;
Pratt, SJ ;
Postlethwait, JH ;
Zon, LI .
GENES & DEVELOPMENT, 1998, 12 (05) :621-626
[8]   A NOVEL, ERYTHROID CELL-SPECIFIC MURINE TRANSCRIPTION FACTOR THAT BINDS TO THE CACCC ELEMENT AND IS RELATED TO THE KRUPPEL FAMILY OF NUCLEAR PROTEINS [J].
MILLER, IJ ;
BIEKER, JJ .
MOLECULAR AND CELLULAR BIOLOGY, 1993, 13 (05) :2776-2786
[9]   Conservation of BMP signaling in zebrafish mesoderm patterning [J].
Nikaido, M ;
Tada, M ;
Saji, T ;
Ueno, N .
MECHANISMS OF DEVELOPMENT, 1997, 61 (1-2) :75-88
[10]   DEFECTIVE HEMATOPOIESIS IN FETAL LIVER RESULTING FROM INACTIVATION OF THE EKLF GENE [J].
NUEZ, B ;
MICHALOVICH, D ;
BYGRAVE, A ;
PLOEMACHER, R ;
GROSVELD, F .
NATURE, 1995, 375 (6529) :316-318