Stochastic spreading of intracellular Ca2+ release

被引：105

作者：

Falcke, M

Tsimring, L

Levine, H

机构：

[1] Univ Calif San Diego, Inst Nonlinear Sci, La Jolla, CA 92093 USA

[2] Univ Calif San Diego, Dept Phys, La Jolla, CA 92093 USA

来源：

PHYSICAL REVIEW E | 2000年 / 62卷 / 02期

关键词：

D O I：

10.1103/PhysRevE.62.2636

中图分类号：

O35 [流体力学]; O53 [等离子体物理学];

学科分类号：

070204 ; 080103 ; 080704 ;

摘要：

We study the spreading of calcium-induced calcium release with the stochastic DeYoung-Keizer-model of the inositol 1,4,5-trisphosphate receptor channel. The model shows a transition from isolated release events to steadily propagating waves with increasing IP3 concentration. A state-stochastic backfiring-was found in the regime of steady propagation. The model can be reduced by an adiabatic elimination of the partial differential equation for the Ca2+ concentration to a lattice of stochastic channel clusters.

引用

页码：2636 / 2643

页数：8

共 36 条

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