Antioxidant phenolic compounds from rhizomes of Polygonum paleaceum

被引：54

作者：

Wang, KJ ^{[1
]}

Zhang, YJ ^{[1
]}

Yang, CR ^{[1
]}

机构：

[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 2005年 / 96卷 / 03期

关键词：

Polygonum paleaceum; Polygonaceae; antioxidant phenols; paleaceolactoside;

D O I：

10.1016/j.jep.2004.09.036

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Polygonum paleaceum Wall. ex Hook. f. is a small herb in Polygonaceae family. In southwest of China, the rhizomes of this plant were used as folk drug for the treatment of chronic gastritis, duodenal ulcers, dysentery, wound, pain, hemorrhage and irregular menstruation. The crude aqueous acetone extract exhibited high antioxidant activity (SC50 = 16.72 mug/ml) in 1, 1-diphenyl-2-picryldydrazyl (DPPH) radical-scavenging assay. With bioactivity-guided fractionations, 14 antioxidant phenolic compounds 1-14 were obtained from the air-dried rhizomes of this plant. Of them. compound 1, a new phenol named paleaceolactoside, was determined to be 3,5-dihydroxyl hexanoic acid 1,5-lactone 3-(6'-o-galloyl)-o-beta-D-glucopyranoside by detailed spectroscopic analysis. The radical-scavenging activity of all the isolated compounds was also described. (C) 2004 Elsevier Ireland Ltd. All rights reserved.

引用

页码：483 / 487

页数：5

共 28 条

[1]

Aviram M, 2000, FREE RADICAL RES, V33, pS85

[2] Isolation and structure elucidation of radical scavengers from Thymus vulgaris leaves [J].