Signal transduction through NF-κB

被引:1055
作者
May, MJ [1 ]
Ghosh, S
机构
[1] Yale Univ, Sch Med, Immunobiol Sect, New Haven, CT 06520 USA
[2] Yale Univ, Sch Med, Howard Hughes Med Inst, Dept Biochem & Mol Biophys, New Haven, CT 06520 USA
来源
IMMUNOLOGY TODAY | 1998年 / 19卷 / 02期
基金
美国国家卫生研究院;
关键词
D O I
10.1016/S0167-5699(97)01197-3
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The inducible transcription factor NF-kappa B plays a central role in the regulation of many immune and inflammatory responses. Advances in our knowledge of the signaling mechanisms that control the activation of NF-kappa B and recent insights into the nature of the I kappa B-kinase represent significant steps forward in understanding this important signaling pathway.
引用
收藏
页码:80 / 88
页数:9
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