Mouse Phenome Database (MPD)

被引:68
作者
Bogue, Molly A. [1 ]
Grubb, Stephen C. [1 ]
Maddatu, Terry P. [1 ]
Bult, Carol J. [1 ]
机构
[1] Jackson Lab, Bar Harbor, ME 04609 USA
基金
美国国家卫生研究院; 美国国家科学基金会; 美国安德鲁·梅隆基金会; 加拿大自然科学与工程研究理事会; 加拿大健康研究院; 英国医学研究理事会;
关键词
D O I
10.1093/nar/gkl1049
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The Mouse Phenome Database (MPD; http://www.jax.org/phenome) is a repository of phenotypic and genotypic data on commonly used and genetically diverse inbred strains of mice. Strain characteristics data are contributed by members of the scientific community. Electronic access to centralized strain data enables biomedical researchers to choose appropriate strains for many systems-based research applications, including physiological studies, drug and toxicology testing and modeling disease processes. MPD provides a community data repository and a platform for data analysis and in silico hypothesis testing. The laboratory mouse is a premier genetic model for understanding human biology and pathology; MPD facilitates research that uses the mouse to identify and determine the function of genes participating in normal and disease pathways.
引用
收藏
页码:D643 / D649
页数:7
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