Sensing behavior of fluorescent cyclodextrin/peptide hybrids bearing a macrocyclic metal complex

被引：16

作者：

Furukawa, S ^{[1
]}

Mihara, H ^{[1
]}

Ueno, A ^{[1
]}

机构：

[1] Tokyo Inst Technol, Dept Bioengn, Grad Sch Biosci & Biotechnol, Yokohama, Kanagawa 2268501, Japan

来源：

MACROMOLECULAR RAPID COMMUNICATIONS | 2003年 / 24卷 / 02期

关键词：

cyclodextrins; fluorescence; host-guest systems; macrocyclic polyamine; peptides;

D O I：

10.1002/marc.200390033

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Two kinds of cyclodextrin/peptide (CD/peptide) hybrids bearing Zn-II-cyclen or cyclen, dansyl and beta-cyclodextrin (beta-CD) units have been synthesized as chemosensors for organic anionic molecules, Zn-II-cyclen serves as a ligand site and beta-CD is a receptor site for guest molecules, wile the dansyl unit acts as a fluorescent probe. Examination of the fluorescence behaviors of these CD/peptides suggested that the hybrid containing Zn2+ has larger binding constants with respect to anionic molecules than that without Zn2+.

引用

页码：202 / 206

页数：5

共 18 条

[11]

2-Z

[12] SOLID-PHASE SYNTHESIS OF PROTECTED PEPTIDE-FRAGMENTS USING A TRIALKOXY-DIPHENYL-METHYLESTER RESIN [J].