Evidence-based management options for women at increased breast/ovarian cancer risk

被引：28

作者：

Pichert, G ^{[1
]}

Bolliger, B ^{[1
]}

Buser, K ^{[1
]}

Pagani, O ^{[1
]}

机构：

[1] Univ Hosp, Dept Med, Div Oncol, Zurich, Switzerland

来源：

ANNALS OF ONCOLOGY | 2003年 / 14卷 / 01期

关键词：

BRCA1; BRCA2; familial risk; hereditary breast cancer; ovarian cancer; prophylactic surgery;

D O I：

10.1093/annonc/mdg030

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Recent developments in our ability to predict breast cancer risk necessitates primary care physicians learn to evaluate breast cancer risk and its importance in shaping decisions concerning surveillance and risk reduction measures. This article reviews the current opinion on risk assessment and management of women with an increased risk of breast/ovarian cancer. Management options are given for women at slightly, moderately and highly elevated breast cancer risk, as well as for BRCA 1/2 carriers, based on currently available evidence.

引用

页码：9 / 19

页数：11

共 103 条

[11] ATM-heterozygous germline mutations contribute to breast cancer-susceptibility [J].

Broeks, A ;

Urbanus, JHM ;

Floore, AN ;

Dahler, EC ;

Klijn, JGM ;

Rutgers, EJT ;

Devilee, P ;

Russell, NS ;

van Leeuwen, FE ;

van't Veer, LJ .

AMERICAN JOURNAL OF HUMAN GENETICS, 2000, 66 (02) :494-500

[12] Recommendations for follow-up care of individuals with an inherited predisposition to cancer .2. BRCA1 and BRCA2 [J].

Burke, W ;

Daly, M ;

Garber, J ;

Botkin, J ;

Kahn, MJE ;

Lynch, P ;

McTierman, A ;

Offit, K ;

Perlman, J ;

Petersen, G ;

Thomson, E ;

Varricchio, C .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1997, 277 (12) :997-1003

[13] Lifetime exercise activity and breast cancer risk among post-menopausal women [J].

Carpenter, CL ;

Ross, RK ;

Paganini-Hill, A ;

Bernstein, L .

BRITISH JOURNAL OF CANCER, 1999, 80 (11) :1852-1858

[14] Mammography in Asian patients with BRCA1 mutations [J].

Chang, J ;

Yang, WT ;

Choo, HF .

LANCET, 1999, 353 (9169) :2070-2071

[15]

Chart PL, 1997, CAN MED ASSOC J, V157, P1235

[16] Primary care: Reducing the risk of breast cancer [J].

Chlebowski, RT .

NEW ENGLAND JOURNAL OF MEDICINE, 2000, 343 (03) :191-198

[17]

CLAUS EB, 1994, CANCER, V73, P643, DOI 10.1002/1097-0142(19940201)73:3<643::AID-CNCR2820730323>3.0.CO

[18]

2-5

[19] Risk of breast cancer in young women in relation to body size and weight gain in adolescence and early adulthood [J].

Coates, RJ ;

Uhler, RJ ;

Hall, HI ;

Potischman, N ;

Brinton, LA ;

Ballard-Barbash, R ;

Gammon, MD ;

Brogan, DR ;

Daling, JR ;

Malone, KE ;

Schoenberg, JB ;

Swanson, CA .

BRITISH JOURNAL OF CANCER, 1999, 81 (01) :167-174

[20] MENOPAUSE AND THE RISK OF CORONARY HEART-DISEASE IN WOMEN [J].

COLDITZ, GA ;

WILLETT, WC ;

STAMPFER, MJ ;

ROSNER, B ;

SPEIZER, FE ;

HENNEKENS, CH .

NEW ENGLAND JOURNAL OF MEDICINE, 1987, 316 (18) :1105-1110

← 1 2 3 4 5 6 7 8 9 10 →