Molecular diagnostics of viral hemorrhagic fevers

被引：105

作者：

Drosten, C ^{[1
]}

Kümmerer, BM ^{[1
]}

Schmitz, H ^{[1
]}

Günther, S ^{[1
]}

机构：

[1] Bernhard Nocht Inst Trop Med, Dept Virol, D-20359 Hamburg, Germany

来源：

ANTIVIRAL RESEARCH | 2003年 / 57卷 / 1-2期

关键词：

viral hemorrhagic fevers; VHF diagnostic tool; molecular diagnostic tool;

D O I：

10.1016/S0166-3542(02)00201-2

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

This review addresses the diagnostics of viral hemorrhagic fevers (VHFs). In the first part, an overview is given on classical methods of VHF diagnostics as well as novel molecular diagnostic tools. Currently available polymerase chain reaction (PCR) assays for diagnosis of VHF are summarized and discussed. In the second part, VHF diagnostics are described in particular for Lassa fever, yellow fever, and Crimean-Congo hemorrhagic fever, based on cases that were imported into or occurred within Europe. The third part is focussed on important differential diagnoses of VHF. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：61 / 87

页数：27

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