Quorum sensin inhibitors from the iced alga, Ahnfeltiopsis flabelliformis

被引:63
作者
Kim, Jung Sun
Kim, Yeon Hee
Seo, Young Wan
Park, Sunghoon [1 ]
机构
[1] Korea Maritime Univ, Div Marine Environm & Biosci, Pusan 606791, South Korea
[2] Dongseo Univ, Dept Biotechnol, Pusan 617716, South Korea
[3] Pusan Natl Univ, Dept Chem & Biochem Engn, Pusan 609735, South Korea
[4] Pusan Natl Univ, Inst Environm Technol & Ind, Pusan 609735, South Korea
关键词
quorum sensing inhibitor; bioassay; AHL inhibitor; Ahnfeltiopsis flabelliformis; Agrobacterium tumefaciens;
D O I
10.1007/BF02931109
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Three new acylhomoserine lactone (AHL) inhibitors have been isolated from the Korean red alga, Ahnfeltiopsis flabelliformis, via bioactivity-guided fractionation using the recombinant Agrobacterium tumefaciens liquid culture bioassay. Unlike the majority of AHL inhibitors reported to date, these compounds were alpha-D-galactopyranosyl-(1 -> 2)-glycerol (floridoside) (1), betonicine (2), and isethionic acid (3), all of which are structurally unrelated to AHLs. (c) KSBB
引用
收藏
页码:308 / 311
页数:4
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