Dax1 is required for testis determination

被引：130

作者：

Meeks, JJ ^{[1
]}

Weiss, J ^{[1
]}

Jameson, JL ^{[1
]}

机构：

[1] Northwestern Univ, Dept Med, Div Endocrinol, Feinberg Sch Med, Chicago, IL 60611 USA

来源：

NATURE GENETICS | 2003年 / 34卷 / 01期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1038/ng1141

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The orphan nuclear receptor, Dax1, was originally proposed to act as an 'anti-testis' factor. We find, however, that Nr0b1 (also called Dax1 and Ahch, which encodes Dax1) is in fact required for testis differentiation.

引用

页码：32 / 33

页数：2

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