An efficient palladium-catalyzed synthesis of unsymmetrical diaryl sulfones from aryl bromides/triflates and arenesulfinates

被引：40

作者：

Cacchi, S ^{[1
]}

Fabrizi, G ^{[1
]}

Goggiamani, A ^{[1
]}

Parisi, LM ^{[1
]}

机构：

[1] Univ Roma La Sapienza, Dipartimento Studi Chim & Tecnol Sostanze Biologi, I-00185 Rome, Italy

来源：

SYNLETT | 2003年 / 03期

关键词：

coupling; sulfones; palladium; catalysis; arenesulfinates;

D O I：

10.1055/s-2003-37117

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The palladium-catalyzed coupling of arenesulfinate salts and aryl bromides or triflates provides a simple and extremely efficient route to unsymmetrical diaryl sulfones. The reaction was found to be strongly influenced by the presence of n-Bu4NCl. The ammonium salt tends to favor the formation of sulfones with neutral, electron-rich and slightly electron-poor aryl bromides or triflates and to hamper the reaction with electron-poor aryl bromides or triflates.

引用

页码：361 / 364

页数：4

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