Spatially addressable multiprotein nanoarrays templated by aptamer-tagged DNA nanoarchitectures

被引：231

作者：

Chhabra, Rahul

Sharma, Jaswinder

Ke, Yonggang

Liu, Yan

Rinker, Sherri

Lindsay, Stuart

Yan, Hao ^{[1
]}

机构：

[1] Arizona State Univ, Dept Chem & Biochem, Tempe, AZ 85287 USA

[2] Arizona State Univ, Biodesign Inst, Tempe, AZ 85287 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 129卷 / 34期

关键词：

D O I：

10.1021/ja072410u

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Here we generalize a highly programmable strategy to self-assemble multiprotein nanoarrays with deterministic positional addressability. These protein nanoarrays were templated by aptamer-tagged DNA nanoarchitectures. Arrays of proteins with precisely controlled positions and interprotein spacings offer great potential in proteomics, tissue engineering, and medical diagnostics.

引用

收藏

页码：10304 / +

页数：3

相关论文

共 25 条

[1] Nanopatterning proteins and peptides [J].

Christman, Karen L. ;

Enriquez-Rios, Vanessa D. ;

Maynard, Heather D. .

SOFT MATTER, 2006, 2 (11) :928-939

[2] INVITRO SELECTION OF RNA MOLECULES THAT BIND SPECIFIC LIGANDS [J].

ELLINGTON, AD ;

SZOSTAK, JW .

NATURE, 1990, 346 (6287) :818-822

[3] DIVERSITY OF OLIGONUCLEOTIDE FUNCTIONS [J].

GOLD, L ;

POLISKY, B ;

UHLENBECK, O ;

YARUS, M .

ANNUAL REVIEW OF BIOCHEMISTRY, 1995, 64 :763-797

[4] Inhibitory DNA ligands to platelet-derived growth factor B-chain [J].

Green, LS ;

Jellinek, D ;

Jenison, R ;

Ostman, A ;

Heldin, CH ;

Janjic, N .

BIOCHEMISTRY, 1996, 35 (45) :14413-14424

[5] Antibody nanoarrays with a pitch of ∼20 nanometers [J].

He, Yu ;

Tian, Ye ;

Ribbe, Alexander E. ;

Mao, Chengde .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (39) :12664-12665

[6] Constructing novel materials with DNA [J].

LaBean, Thom H. ;

Li, Hanying .

NANO TODAY, 2007, 2 (02) :26-35

[7] DNA-templated self-assembly of metallic nanocomponent arrays on a surface [J].

Le, JD ;

Pinto, Y ;

Seeman, NC ;

Musier-Forsyth, K ;

Taton, TA ;

Kiehl, RA .

NANO LETTERS, 2004, 4 (12) :2343-2347

[8] Protein nanoarrays generated by dip-pen nanolithography [J].

Lee, KB ;

Park, SJ ;

Mirkin, CA ;

Smith, JC ;

Mrksich, M .

SCIENCE, 2002, 295 (5560) :1702-1705

[9] Single-chain antibodies against DNA aptamers for use as adapter molecules on DNA tile arrays in nanoscale materials organization [J].

Li, Hanying ;

LaBean, Thomas H. ;

Kenan, Daniel J. .

ORGANIC & BIOMOLECULAR CHEMISTRY, 2006, 4 (18) :3420-3426

[10] Self-assembled signaling aptamer DNA arrays for protein detection [J].

Lin, Chenxiang ;

Katilius, Evaldas ;

Liu, Yan ;

Zhang, Junping ;

Yan, Hao .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (32) :5296-5301