VEGF gene therapy: stimulating angiogenesis or angioma-genesis?

被引:305
作者
Carmeliet, P [1 ]
机构
[1] Katholieke Univ Leuven, Ctr Transgene Technol & Gene Therapy, B-3000 Louvain, Belgium
关键词
D O I
10.1038/80430
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 [生物化学与分子生物学]; 081704 [应用化学];
摘要
The finding that unregulated, continuous delivery of vascular endothelial growth factor to the myocardium causes the formation of hemangiomas and death in mice indicates that more research is required on this potent molecule before clinical trials can proceed.
引用
收藏
页码:1102 / 1103
页数:2
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