JAK2 mutation and disease phenotype: a double L611V/V617F in cis mutation of JAK2 is associated with isolated erythrocytosis and increased activation of AKT and ERK1/2 rather than STAT5

被引：22

作者：

Cleyrat, C. ^{[1
]}

Jelinek, J. ^{[2
]}

Girodon, F. ^{[3
]}

Boissinot, M. ^{[1
]}

Ponge, T. ^{[4
]}

Harousseau, J-L ^{[2
]}

Issa, J-P ^{[2
]}

Hermouet, S. ^{[1
,5
]}

机构：

[1] Univ Nantes, IRT, INSERM, CRCNA,UMR 892, Nantes, France

[2] Univ Texas MD Anderson Canc Ctr, Dept Leukemia, Houston, TX 77030 USA

[3] CHU, Hematol Lab, Dijon, France

[4] CHU, Serv Med Interne, Nantes, France

[5] CHU, Inst Biol, Hematol Lab, Nantes, France

来源：

LEUKEMIA | 2010年 / 24卷 / 05期

关键词：

POLYCYTHEMIA-VERA; JAK2-V617F;

D O I：

10.1038/leu.2010.23

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：1069 / 1073

页数：6

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