Guilt beyond a reasonable doubt

被引：105

作者：

Altshuler, David ^{[1
]}

Daly, Mark

机构：

[1] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Boston, MA 02115 USA

[2] Harvard Univ, Broad Inst, Boston, MA 02115 USA

[3] MIT, Broad Inst, Boston, MA USA

来源：

NATURE GENETICS | 2007年 / 39卷 / 07期

关键词：

GENOME-WIDE ASSOCIATION; SUSCEPTIBILITY; VARIANTS; MULTIPLE; IL23R; LOCI; GENE;

D O I：

10.1038/ng0707-813

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Genome-wide association studies, exemplified by the Wellcome Trust Case Control Consortium and follow-up studies, have identified dozens of common variants robustly associated with common diseases, providing new clues about genetic architecture in humans. Finding all such loci, and fully defining genotype-phenotype correlation, will be a key to translating initial clues into pathophysiological understanding and clinical prediction.

引用

页码：813 / 815

页数：4

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