Type II DNA topoisomerases

被引：63

作者：

Berger, JM ^{[1
]}

机构：

[1] Whitehead Inst, Cambridge, MA 02142 USA

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1998年 / 8卷 / 01期

关键词：

D O I：

10.1016/S0959-440X(98)80006-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Type II DNA topoisomerases are enzymes capable of passing one DNA duplex through another. A combination of structural and biochemical analyses is illuminating the mechanistic details of this transport reaction, revealing the sites of DNA and nucleotide binding and the existence of large-scale domain motions.

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页码：26 / 32

页数：7

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