Preparation of homochiral (S)- and (R)-1-(2-furyl)ethanols by lipase-catalyzed transesterification

被引：26

作者：

Kaminska, J

Gornicka, I

Sikora, M

Gora, J

机构：

[1] Institute of General Food Chemistry, Tech. Univ. of Łodz, 90-924 Łódź

来源：

TETRAHEDRON-ASYMMETRY | 1996年 / 7卷 / 03期

关键词：

D O I：

10.1016/0957-4166(96)00088-2

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

1-(2-Furyl)ethanol 1 was resolved by irreversible transesterification with vinyl acetate using Lipozyme IM or Porcine Pancreas Lipase (PPL) in an organic solvent. (S)-alcohol (99% e.e.) was obtained in 80-85% yield using Lipozyme IM in carbon tetrachloride while (R)-1-(2-furyl)ethyl acetate (96% e.e.) in 75-80% yield resulted from transesterification using Lipozyme IM in hexane or PPL in tetrahydrofuran. (C) 1996 Elsevier Science Ltd

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页码：907 / 910

页数：4

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