Polyprotein processing protease of African swine fever virus:: Purification and biochemical characterization

被引：11

作者：

Rubio, D ^{[1
]}

Alejo, A ^{[1
]}

Rodríguez, I ^{[1
]}

Salas, ML ^{[1
]}

机构：

[1] Univ Autonoma Madrid, Fac Ciencias, CSIC, Ctr Biol Mol Severo Ochoa, E-28049 Madrid, Spain

来源：

JOURNAL OF VIROLOGY | 2003年 / 77卷 / 07期

关键词：

D O I：

10.1128/JVI.77.7.4444-4448.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The purified recombinant African swine fever virus polyprotein processing protease cleaves the two GG-X sites in polyprotein pp62 with the same efficiency. Cleavage at the site that is first recognized in vivo is not a requisite for cleavage at the second site, suggesting the existence of mechanisms that control the ordered processing of the polyprotein during infection.

引用

页码：4444 / 4448

页数：5

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