Elimination of electrochemical interferences in glucose biosensors

被引：84

作者：

Jia, Wen-Zhi ^{[1
]}

Wang, Kang ^{[1
]}

Xia, Xing-Hua ^{[1
]}

机构：

[1] Nanjing Univ, Sch Chem & Chem Engn, Key Lab Analyt Chem Life Sci, Nanjing 210093, Peoples R China

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2010年 / 29卷 / 04期

基金：

中国国家自然科学基金;

关键词：

Amperometric biosensor; Electrochemical analysis; Enzyme; Glucose; Glucose biosensor; Glucose oxidase; Horseradish peroxidase; Interference; Scanning electrochemical microscopy; Selectivity; GLASSY-CARBON ELECTRODE; BLUE MODIFIED ELECTRODES; CELLULOSE-ACETATE MEMBRANES; HYDROGEN-PEROXIDE DETECTION; POLYION COMPLEX MEMBRANE; PRUSSIAN-BLUE; ENZYME ELECTRODES; DIFFUSION LAYER; AMPEROMETRIC DETERMINATION; ASCORBIC-ACID;

D O I：

10.1016/j.trac.2010.01.006

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

As classical biosensing systems, amperometric glucose biosensors have been widely studied and developed since Clark and Lyons first proposed the concept of glucose-enzyme electrodes in 1962. Although glucose oxidase can selectively and specifically catalyze oxidation of glucose, amperometric detection can hardly distinguish the current generated by the enzymatic reaction from the currents generated by electroactive species in biological samples. Various methods have therefore been reported to improve the overall selectivity of enzyme-based biosensors. This review summarizes the methods developed for eliminating electrochemical interferences. We emphasize our efforts to improve the performance of biosensors. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：306 / 318

页数：13

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