Antidepressant effects of Banxia Houpu decoction, a traditional Chinese medicinal empirical formula

被引：94

作者：

Luo, L ^{[1
]}

Wang, JN ^{[1
]}

Kong, LD ^{[1
]}

Jiang, QG ^{[1
]}

Tan, RX ^{[1
]}

机构：

[1] Nanjing Univ, Sch Life Sci, State Key Lab Pharmaceut Biotechnol, Inst Funct Biomol, Nanjing 210093, Peoples R China

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 2000年 / 73卷 / 1-2期

基金：

中国国家自然科学基金;

关键词：

Pinellia ternata; Magnolia officinalis; Poria cocos; Perilla frutescens; Zingiber officinale; Banxia Houpu decoction; antidepressant action;

D O I：

10.1016/S0378-8741(00)00242-7

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Banxia Houpu Decoction, having been used for the treatment of depression-related diseases since ancient times, is a traditional Chinese medicinal empirical formula consisting of Pinellia ternata, Poria cocos, Magnolia officinalis, Perilla frutescens and Zingiber officinale. The effects of the total decoction extract and five fractions therefrom. were evaluated in mice by tail suspension and forced swimming tests. The total 90% ethanol extract of the decoction was shown to possess an antidepressant activity that was close to that of Prozac, an antidepressant agent being applied clinically. Furthermore, the active principles were demonstrated to be mainly in the aqueous (Bx4) and lipophic (Bx5) parts of the decoction extract while the polyphenol fraction (Bx2) exhibited a moderate action. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：277 / 281

页数：5

共 9 条

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