A synthesis of cyclo-2,3-diphospho-D-glycerate from D-mannitol

被引：3

作者：

Berkessel, A

Geisel, U

Herault, DA

机构：

[1] Organisch-Chemisches Institut, Ruprecht-Karls-Univ. Heidelberg, D-69120 Heidelberg

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 03期

关键词：

D O I：

10.1016/0040-4039(95)02154-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

cyclo-2,3-Diphospho-D-glycerate (c-DPG) was synthesized from D-mannitol in seven steps on a gram-scale. Key feature of the synthetic route is the cyclization of methyl 2,3-diphospho-D-glycerate using dicyclohexylcarbodiimide. The preparation described makes the natural product c-DPG available on a larger scale for the first time.

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页码：355 / 356

页数：2

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