We study a physical system which, while devoid of the complexity one usually associates with proteins, nevertheless displays a remarkable array of proteinlike properties. The constructive hypothesis that this striking resemblance is not accidental not only leads to a unified framework for understanding protein folding, amyloid formation, and protein interactions but also has implications for natural selection.
机构:Univ Calif San Francisco, Program Biol & Med Informat, San Francisco, CA 94143 USA
Goh, CS
;
Cohen, FE
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机构:
Univ Calif San Francisco, Program Biol & Med Informat, San Francisco, CA 94143 USAUniv Calif San Francisco, Program Biol & Med Informat, San Francisco, CA 94143 USA
机构:Univ Calif San Francisco, Program Biol & Med Informat, San Francisco, CA 94143 USA
Goh, CS
;
Cohen, FE
论文数: 0引用数: 0
h-index: 0
机构:
Univ Calif San Francisco, Program Biol & Med Informat, San Francisco, CA 94143 USAUniv Calif San Francisco, Program Biol & Med Informat, San Francisco, CA 94143 USA