Sex releases the speed limit on evolution

被引：183

作者：

Colegrave, N ^{[1
]}

机构：

[1] Univ Edinburgh, Inst Cell Anim & Populat Biol, Edinburgh EH9 3JT, Midlothian, Scotland

来源：

NATURE | 2002年 / 420卷 / 6916期

基金：

英国生物技术与生命科学研究理事会;

关键词：

D O I：

10.1038/nature01191

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Explaining the evolutionary maintenance of sex remains a key problem in evolutionary biology(1-3). One potential benefit of sex is that it may allow a more rapid adaptive response when environmental conditions change, by increasing the efficiency with which selection can fix beneficial mutations(4-7). Here I show that sex can increase the rate of adaptation in the facultatively sexual single-celled chlorophyte Chlamydomonas reinhardtii, but that the benefits of sex depend crucially on the size of the population that is adapting: sex has a marked effect in large populations but little effect in small populations. Several mechanisms have been proposed to explain the benefits of sex in a novel environment, including stochastic effects in small populations, clonal interference and epistasis between beneficial alleles. These results indicate that clonal interference is important in this system.

引用

页码：664 / 666

页数：3

共 15 条

[1]

Bell G, 1982, Ethol Sociobiol

[2]

Burt A, 2000, EVOLUTION, V54, P337

[3]

Colegrave N, 2002, EVOLUTION, V56, P14

[4] Diminishing returns from mutation supply rate in asexual populations [J].

de Visser, JAGM ;

Zeyl, CW ;

Gerrish, PJ ;

Blanchard, JL ;

Lenski, RE .

SCIENCE, 1999, 283 (5400) :404-406

[5]

Fisher R., 2005, TEACHING CHILDREN TH, V2nd

[6] The fate of competing beneficial mutations in an asexual population [J].

Gerrish, PJ ;

Lenski, RE .

GENETICA, 1998, 102-3 (0) :127-144

[7] Mild environmental stress elicits mutations affecting fitness in Chlamydomonas [J].

Goho, S ;

Bell, G .

PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2000, 267 (1439) :123-129

[8] LONG-TERM EXPERIMENTAL EVOLUTION IN ESCHERICHIA-COLI .1. ADAPTATION AND DIVERGENCE DURING 2,000 GENERATIONS [J].

LENSKI, RE ;

ROSE, MR ;

SIMPSON, SC ;

TADLER, SC .

AMERICAN NATURALIST, 1991, 138 (06) :1315-1341

[9]

Maynard Smith J., 1978, EVOLUTION SEX

[10] Clonal interference and the evolution of RNA viruses [J].

Miralles, R ;

Gerrish, PJ ;

Moya, A ;

Elena, SF .

SCIENCE, 1999, 285 (5434) :1745-1747

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