Getting to the root of plant biology: impact of the Arabidopsis genome sequence on root research

被引:50
作者
Benfey, Philip N. [1 ]
Bennett, Malcolm [2 ]
Schiefelbein, John [3 ]
机构
[1] Duke Univ, Dept Biol, Inst Genome Sci & Policy, Ctr Syst Biol, Durham, NC 27710 USA
[2] Univ Nottingham, Ctr Plant Integrat Biol, Sch Biosci, Nottingham NG7 2RD, England
[3] Univ Michigan, Dept Mol Cellular & Dev Biol, Ann Arbor, MI 48109 USA
基金
英国生物技术与生命科学研究理事会; 英国工程与自然科学研究理事会; 美国国家科学基金会;
关键词
Arabidopsis; root biology; genomics; development; genetics; transcriptome; EPIDERMAL-CELL DIFFERENTIATION; TRANSCRIPTION FACTOR; INTERCELLULAR MOVEMENT; CAPRICE TRANSCRIPTION; SYSTEM ARCHITECTURE; HAIR DEVELOPMENT; AUXIN TRANSPORT; GENE-EXPRESSION; THALIANA; PROTEIN;
D O I
10.1111/j.1365-313X.2010.04129.x
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
P>Prior to the availability of the genome sequence, the root of Arabidopsis had attracted a small but ardent group of researchers drawn to its accessibility and developmental simplicity. Roots are easily observed when grown on the surface of nutrient agar media, facilitating analysis of responses to stimuli such as gravity and touch. Developmental biologists were attracted to the simple radial organization of primary root tissues, which form a series of concentric cylinders around the central vascular tissue. Equally attractive was the mode of propagation, with stem cells at the tip giving rise to progeny that were confined to cell files. These properties of root development reduced the normal four-dimensional problem of development (three spatial dimensions and time) to a two-dimensional problem, with cell type on the radial axis and developmental time along the longitudinal axis. The availability of the complete Arabidopsis genome sequence has dramatically accelerated traditional genetic research on root biology, and has also enabled entirely new experimental strategies to be applied. Here we review examples of the ways in which availability of the Arabidopsis genome sequence has enhanced progress in understanding root biology.
引用
收藏
页码:992 / 1000
页数:9
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