From capped to three-dimensional cyclodextrins:: the first example of a new class of receptors by trehalose capping of a β-cyclodextrin

被引：18

作者：

Cucinotta, V

Grasso, G

Vecchio, G

机构：

[1] Univ Naples Federico II, Dipartimento Sci Alimenti, I-80055 Napoli, Italy

[2] CNR, Ist Studio Sostanze Nat Interesse Alimentare & Ch, I-95125 Catania, Italy

[3] Univ Catania, Dipartimento Sci Chim, I-95125 Catania, Italy

来源：

JOURNAL OF INCLUSION PHENOMENA AND MOLECULAR RECOGNITION IN CHEMISTRY | 1998年 / 31卷 / 01期

关键词：

cyclodextrins; capped cyclodextrins; inclusion; trehalose;

D O I：

10.1023/A:1007994324973

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new capped derivative of cyclomaltoheptaose (CDTHCM) was synthesized by the reaction of 6,6'-dideoxy-6,6' -di(S-cysteamine)-alpha,alpha'-trehalose with 6A,6D-dideoxy-6A,6D-diiodo-cyclomaltoheptaose. The CDTHCM obtained was characterized, together with its behaviour towards protonation. The CDTHCM/ACS (anthraquinone-2-sulfonic acid sodium salt) system was investigated by (HNMR)-H-1 spectroscopy and by i.c.d. (induced circular dichroism) at two different pHs. The deep inclusion of ACS within the CDTHCM cavity, with an association constant about six times larger compared to the beta-CD/ACS system was found at pH 6.

引用

页码：43 / 55

页数：13

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