Error-prone candidates vie for somatic mutation

被引：52

作者：

Poltoratsky, V

Goodman, MF

Scharff, MD

机构：

[1] Yeshiva Univ Albert Einstein Coll Med, Dept Cell Biol, Bronx, NY 10461 USA

[2] Univ So Calif, Dept Chem & Biol Sci, Los Angeles, CA 90089 USA

来源：

JOURNAL OF EXPERIMENTAL MEDICINE | 2000年 / 192卷 / 10期

关键词：

D O I：

10.1084/jem.192.10.F27

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：F27 / F30

页数：4

共 32 条

[21] Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting [J].

Rada, C ;

Ehrenstein, MR ;

Neuberger, MS ;

Milstein, C .

IMMUNITY, 1998, 9 (01) :135-141

[22] Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the hyper-IgM syndrome (HIGM2) [J].

Revy, P ;

Muto, T ;

Levy, Y ;

Geissmann, F ;

Plebani, A ;

Sanal, O ;

Catalan, N ;

Forveille, M ;

Dufourcq-Lagelouse, R ;

Gennery, A ;

Tezcan, I ;

Ersoy, F ;

Kayserili, H ;

Ugazio, AG ;

Brousse, N ;

Muramatsu, M ;

Notarangelo, LD ;

Kinoshita, K ;

Honjo, T ;

Fischer, A ;

Durandy, A .

CELL, 2000, 102 (05) :565-575

[23] TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line [J].

Sale, JE ;

Neuberger, MS .

IMMUNITY, 1998, 9 (06) :859-869

[24] Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes [J].

Schrader, CE ;

Edelmann, W ;

Kucherlapati, R ;

Stavnezer, J .

JOURNAL OF EXPERIMENTAL MEDICINE, 1999, 190 (03) :323-330

[25] Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes [J].

Shen, HM ;

Peters, A ;

Baron, B ;

Zhu, XD ;

Storb, U .

SCIENCE, 1998, 280 (5370) :1750-1752

[26] Mechanism of antigen-driven somatic hypermutation of rearranged immunoglobulin V(D)J genes in the mouse [J].

Steele, EJ ;

Rothenfluh, HS ;

Blanden, RV .

IMMUNOLOGY AND CELL BIOLOGY, 1997, 75 (01) :82-95

[27] Progress in understanding the mechanism and consequences of somatic hypermutation [J].

Storb, U .

IMMUNOLOGICAL REVIEWS, 1998, 162 :5-11

[28] Roles of E-coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesis [J].

Tang, MJ ;

Pham, P ;

Shen, X ;

Taylor, JS ;

O'Donnell, M ;

Woodgate, R ;

Goodman, MF .

NATURE, 2000, 404 (6781) :1014-1018

[29]

Tissier A, 2000, GENE DEV, V14, P1642

[30] Somatic hypermutation, transcription, and DNA mismatch repair [J].

Wiesendanger, M ;

Scharff, MD ;

Edelmann, W .

CELL, 1998, 94 (04) :415-418

← 1 2 3 4 →