Potential oncogene activity of the woodchuck hepatitis post-transcriptional regulatory element (WPRE)

被引：68

作者：

Kingsman, SM

Mitrophanous, K

Olsen, JC

机构：

[1] Oxford BioMedica UK Ltd, Medawar Ctr, Oxford OX4 4GA, England

[2] Univ N Carolina, Cyst Fibrosis Pulm Res & Treatment Ctr, Chapel Hill, NC USA

来源：

GENE THERAPY | 2005年 / 12卷 / 01期

关键词：

D O I：

10.1038/sj.gt.3302417

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：3 / 4

页数：2

共 15 条

[1] Neuroprotection in a rat Parkinson model by GDNF gene therapy using EIAV vector [J].

Azzouz, M ;

Ralph, S ;

Wong, LF ;

Day, D ;

Askham, Z ;

Barber, RD ;

Mitrophanous, KA ;

Kingsman, SM ;

Mazarakis, ND .

NEUROREPORT, 2004, 15 (06) :985-990

[2] Long-term replacement of a mutated nonfunctional CNS gene: Reversal of hypothalamic diabetes insipidus using an EIAV-based lentiviral vector expressing arginine vasopressin [J].

Bienemann, AS ;

Martin-Rendon, E ;

Cosgrave, AS ;

Glover, CPJ ;

Wong, LF ;

Kingsman, SM ;

Mitrophanous, KA ;

Mazarakis, ND ;

Uney, JB .

MOLECULAR THERAPY, 2003, 7 (05) :588-596

[3] Woodchuck hepatitis virus contains a tripartite posttranscriptional regulatory element [J].

Donello, JE ;

Loeb, JE ;

Hope, TJ .

JOURNAL OF VIROLOGY, 1998, 72 (06) :5085-5092

[4] Woodchuck hepatitis virus enhancer I and enhancer II are both involved in N-myc2 activation in woodchuck liver tumors [J].

Flajolet, M ;

Tiollais, P ;

Buendia, MA ;

Fourel, G .

JOURNAL OF VIROLOGY, 1998, 72 (07) :6175-6180

[5] MALIGNANT TRANSFORMATION OF IMMORTALIZED TRANSGENIC HEPATOCYTES AFTER TRANSFECTION WITH HEPATITIS-B VIRUS-DNA [J].

HOHNE, M ;

SCHAEFER, S ;

SEIFER, M ;

FEITELSON, MA ;

PAUL, D ;

GERLICH, WH .

EMBO JOURNAL, 1990, 9 (04) :1137-1145

[6] X-gene product of hepatitis B virus induces apoptosis in liver cells [J].

Kim, H ;

Lee, H ;

Yun, Y .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (01) :381-385

[7] Enhanced expression of transgenes from adeno-associated virus vectors with the woodchuck hepatitis virus posttranscriptional regulatory element: Implications for gene therapy [J].

Loeb, JE ;

Cordier, WS ;

Harris, ME ;

Weitzman, MD ;

Hope, TJ .

HUMAN GENE THERAPY, 1999, 10 (14) :2295-2305

[8]

MURAKAMI S, 1994, J BIOL CHEM, V269, P15118

[9] Hepatocyte-specific gene expression from integrated lentiviral vectors [J].

Nash, KL ;

Jamil, B ;

Maguire, AJ ;

Alexander, GJM ;

Lever, AML .

JOURNAL OF GENE MEDICINE, 2004, 6 (09) :974-983

[10] Analysis of gene transfer and expression in skeletal muscle using enhanced EIAV lentivirus vectors [J].

O'Rourke, JP ;

Hiraragi, H ;

Urban, K ;

Patel, M ;

Olsen, JC ;

Bunnell, BA .

MOLECULAR THERAPY, 2003, 7 (05) :632-639

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