A new triterpenoid ester from the fruits of Bruguiera parviflora

被引：27

作者：

Chumkaew, P

Kato, S

Chantrapromma, K ^{[1
]}

机构：

[1] Walailak Univ, Sch Sci, Nakhon Si Thammarat 80160, Taiwan

[2] Seikei Univ, Fac Engn, Dept Appl Chem, Musashino, Tokyo 1808633, Japan

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2005年 / 53卷 / 01期

关键词：

Bruguiera parviflora; rhizophoraceae; triterpenoid ester; antimalarial;

D O I：

10.1248/cpb.53.95

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A new lupane caffeoyl ester (1), 3-(Z)-caffeoyllupeol, together with five known triterpenoids, lupeol caffeate (2), 3-(Z)-coumaroyllupeol (3), dioslupecin A (4), lupeol (5), and lupenone (6), were isolated from the fruits of Bruguiera parviflora. Their structures were elucidated by spectroscopic methods. Compound 1 exhibited antimalarial activity with an EC50 value of 8.6 mug/ml, but compound 2 was inactive.

引用

页码：95 / 96

页数：2

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