Accurate measurement of longitudinal cross-relaxation rates in nuclear magnetic resonance

被引：28

作者：

Pelupessy, Philippe

Ferrage, Fabien

Bodenhausen, Geoffrey

机构：

[1] Ecole Normale Super, CNRS, Dept Chim, F-75231 Paris 05, France

[2] Ecole Polytech Fed Lausanne, Lab Resonance Magnet Biomol, CH-1015 Lausanne, Switzerland

来源：

JOURNAL OF CHEMICAL PHYSICS | 2007年 / 126卷 / 13期

关键词：

D O I：

10.1063/1.2715583

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The accuracy of the determination of longitudinal cross-relaxation rates in NMR can be improved by combining symmetrical reconversion with suitable operator swapping methods that lead to the averaging of differences in autorelaxation rates and eliminate the effects of cross relaxation with the environment. The principles are first discussed for an isolated two-spin system comprising a pair of N-15 and H-1(N) nuclei subjected to chemical shift anisotropy and dipole-dipole relaxation, and then extended to include further protons. The gains in accuracy are demonstrated experimentally for the protein ubiquitin. (c) 2007 American Institute of Physics.

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页数：10

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