Commentary on "Cannabinoids modulate pain by multiple mechanisms of action"

被引：12

作者：

Ward, SJ ^{[1
]}

机构：

[1] Wyeth Ayerst Res, Radnor, PA 19087 USA

来源：

JOURNAL OF PAIN | 2000年 / 1卷 / 01期

关键词：

D O I：

10.1016/S1526-5900(00)90083-X

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Dr. Richardson's stimulating review should help spur investigations to address remaining unanswered questions and promote the much-needed political debate on the medicinal value of cannabinoids, without which pharmaceutical development of cannabinoid drugs will continue to be hampered.

引用

收藏

页码：15 / 17

页数：3

相关论文

共 21 条

[1] COMPARISON OF SOME PHARMACOLOGICAL ACTIONS OF MORPHINE AND DELTA-9-TETRAHYDROCANNABINOL IN MOUSE [J].

BLOOM, AS ;

DEWEY, WL .

PSYCHOPHARMACOLOGY, 1978, 57 (03) :243-248

[2] Control of pain initiation by endogenous cannabinoids [J].

Calignano, A ;

La Rana, G ;

Giuffrida, A ;

Piomelli, D .

NATURE, 1998, 394 (6690) :277-281

[3] Activation of corticotropin-releasing factor in the limbic system during cannabinoid withdrawal [J].

deFonseca, FR ;

Carrera, MRA ;

Navarro, M ;

Koob, GF ;

Weiss, F .

SCIENCE, 1997, 276 (5321) :2050-2054

[4]

Dehaven-Hudkins DL, 1999, J PHARMACOL EXP THER, V289, P494

[5] RESEARCH-AND-DEVELOPMENT COSTS FOR NEW DRUGS BY THERAPEUTIC CATEGORY - A STUDY OF THE UNITED-STATES PHARMACEUTICAL-INDUSTRY [J].

DIMASI, JA ;

HANSEN, RW ;

GRABOWSKI, HG ;

LASAGNA, L .

PHARMACOECONOMICS, 1995, 7 (02) :152-169

[6] The analgesic effects of R(+)-WIN 55,212-2 mesylate, a high affinity cannabinoid agonist, in a rat model of neuropathic pain [J].

Herzberg, U ;

Eliav, E ;

Bennett, GJ ;

Kopin, IJ .

NEUROSCIENCE LETTERS, 1997, 221 (2-3) :157-160

[7] The anti-hyperalgesic actions of the cannabinoid anandamide and the putative CB2 receptor agonist palmitoylethanolamide in visceral and somatic inflammatory pain [J].

Jaggar, SI ;

Hasnie, FS ;

Sellaturay, S ;

Rice, ASC .

PAIN, 1998, 76 (1-2) :189-199

[8]

KENAKIN TP, 1987, PHARM ANAL DRUG RECE, P245

[9] Pathophysiology of joint pain [J].

Kidd, BL ;

Morris, VH ;

Urban, L .

ANNALS OF THE RHEUMATIC DISEASES, 1996, 55 (05) :276-283

[10] Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice [J].

Ledent, C ;

Valverde, O ;

Cossu, C ;

Petitet, F ;

Aubert, LF ;

Beslot, F ;

Böhme, GA ;

Imperato, A ;

Pedrazzini, T ;

Roques, BP ;

Vassart, G ;

Fratta, W ;

Parmentier, M .

SCIENCE, 1999, 283 (5400) :401-404