More GABA, less distraction: a neurochemical predictor of motor decision speed

被引：128

作者：

Sumner, Petroc ^{[1
]}

Edden, Richard A. E. ^{[1
,2
,3
]}

Bompas, Aline ^{[1
]}

Evans, C. John ^{[1
]}

Singh, Krish D. ^{[1
]}

机构：

[1] Cardiff Univ, Sch Psychol, Brain Res Imaging Ctr, Cardiff, S Glam, Wales

[2] Johns Hopkins Univ, Russell H Morgan Dept Radiol & Radiol Sci, Baltimore, MD USA

[3] Kennedy Krieger Inst, FM Kirby Res Ctr Funct Magnet Resonance Imaging, Baltimore, MD USA

来源：

NATURE NEUROSCIENCE | 2010年 / 13卷 / 07期

基金：

英国生物技术与生命科学研究理事会; 英国惠康基金;

关键词：

CORTEX;

D O I：

10.1038/nn.2559

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

People vary markedly in the efficiency with which they can resolve competitive action decisions, even simple ones such as shifting gaze to one stimulus rather than another. We found that an individual's ability to rapidly resolve such competition is predicted by the concentration of GABA, the main inhibitory neurotransmitter, in a region of frontal cortex that is relevant for eye movements, but not in a control region (occipital cortex).

引用

页码：825 / 827

页数：3

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